Invention Grant
US09173879B2 Crystalline forms of (S)-7-([1,2,4]triazolo[1,5-a ]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline and use thereof
有权
（S）-7 - （[1,2,4]三唑并[1,5-a]吡啶-6-基）-4-（3,4-二氯苯基）-1,2,3,4-四氢异喹啉的结晶形式 四氢异喹啉及其用途
![Crystalline forms of (S)-7-([1,2,4]triazolo[1,5-a ]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline and use thereof](/docs/US/2015-11-03/US09173879B2/abs.jpg.600x600.jpg)
- Patent Title: Crystalline forms of (S)-7-([1,2,4]triazolo[1,5-a ]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline and use thereof
- Patent Title (中): （S）-7 - （[1,2,4]三唑并[1,5-a]吡啶-6-基）-4-（3,4-二氯苯基）-1,2,3,4-四氢异喹啉的结晶形式 四氢异喹啉及其用途
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Application No.: US14466009Application Date: 2014-08-22
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Publication No.: US09173879B2Publication Date: 2015-11-03
- Inventor: Chenkou Wei , Victor W. Rosso , Qi Gao
- Applicant: Bristol-Myers Squibb Company
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agency: LeClairRyan, a Professional Corporation
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K31/495 ; A61K31/4725 ; A61K31/437 ; A61K31/438 ; A61K45/06
![Crystalline forms of (S)-7-([1,2,4]triazolo[1,5-a ]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline and use thereof](/abs-image/US/2015/11/03/US09173879B2/abs.jpg.150x150.jpg)
Abstract:
Novel [1,2,4]triazolo[1,5-a]pyridinyl-6-yl-substituted tetrahydroisoquinolines are described in the present invention. These compounds and crystalline forms SA1 and N-2 are used in the treatment of various neurological and physiological disorders. Methods of making these compounds and crystalline forms SA-1 and N-2 are also described in the present invention.
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