Invention Grant
- Patent Title: Ring-substituted N-pyridinyl amides as kinase inhibitors
- Patent Title (中): 环取代的N-吡啶基酰胺作为激酶抑制剂
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Application No.: US14402541Application Date: 2013-05-20
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Publication No.: US09173883B2Publication Date: 2015-11-03
- Inventor: Matthew Burger , Joseph E. Drumm, III , Gisele Nishiguchi , Alice Rico , Robert Lowell Simmons , Benjamin Taft , Huw Tanner
- Applicant: Novartis AG
- Applicant Address: CH Basel
- Assignee: NOVARTIS AG
- Current Assignee: NOVARTIS AG
- Current Assignee Address: CH Basel
- Agent Rona Nardone
- International Application: PCT/IB2013/054145 WO 20130520
- International Announcement: WO2013/175388 WO 20131128
- Main IPC: C07D403/12
- IPC: C07D403/12 ; C07D401/14 ; C07D401/12 ; C07D403/14 ; C07D407/14 ; C07D409/14 ; C07D417/12 ; C07D417/14 ; C07D213/81 ; C07D405/14 ; A61K31/506 ; A61K31/4439 ; A61K31/444 ; A61K31/4545 ; A61K31/675 ; A61K45/06 ; C07F9/6558
Abstract:
The present invention provides a compound of formula (A): as described herein, and pharmaceutically acceptable salts, enantiomers, rotamers, tautomers, or racemates thereof. Also provided are methods of treating a disease or condition mediated by PIM kinase using the compounds of Formula I, and pharmaceutical compositions comprising such compounds.
Public/Granted literature
- US20150133473A1 NOVEL RING-SUBSTITUTED N-PYRIDINYL AMIDES AS KINASE INHIBITORS Public/Granted day:2015-05-14
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