Invention Grant
US09174965B2 Pyrimidinylpiperidinyloxypyridone analogues as GPR119 modulators
有权
嘧啶基哌啶氧基吡啶酮类似物作为GPR119调节剂
- Patent Title: Pyrimidinylpiperidinyloxypyridone analogues as GPR119 modulators
- Patent Title (中): 嘧啶基哌啶氧基吡啶酮类似物作为GPR119调节剂
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Application No.: US14400758Application Date: 2013-05-13
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Publication No.: US09174965B2Publication Date: 2015-11-03
- Inventor: Matthias Broekema , Gang Wu , Dean A. Wacker
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Barry H. Jacobsen
- International Application: PCT/US2013/040692 WO 20130513
- International Announcement: WO2013/173198 WO 20131121
- Main IPC: C07D401/14
- IPC: C07D401/14 ; A61K31/506 ; A61K31/403

Abstract:
Novel compounds of structure Formula I: (I) or an enantiomer, a diastereomer, or a pharmaceutically acceptable salt thereof, wherein R1, R2 and R3 are defined herein, are provided which are GPR119 G protein-coupled receptor modulators. GPR119 G protein-coupled receptor modulators are useful in treating, preventing, or slowing the progression of diseases requiring GPR119 G protein-coupled receptor modulator therapy. Thus, the disclosure also concerns compositions comprising these novel compounds and methods of treating diseases or conditions related to the activity of the GPR119 G protein-coupled receptor by using any of these novel compounds or a composition comprising any of such novel compounds.
Public/Granted literature
- US20150133479A1 PYRIMIDINYLPIPERIDINYLOXYPYRIDONE ANALOGUES AS GPR119 MODULATORS Public/Granted day:2015-05-14
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