Invention Grant
US09174965B2 Pyrimidinylpiperidinyloxypyridone analogues as GPR119 modulators 有权
嘧啶基哌啶氧基吡啶酮类似物作为GPR119调节剂

Pyrimidinylpiperidinyloxypyridone analogues as GPR119 modulators
Abstract:
Novel compounds of structure Formula I: (I) or an enantiomer, a diastereomer, or a pharmaceutically acceptable salt thereof, wherein R1, R2 and R3 are defined herein, are provided which are GPR119 G protein-coupled receptor modulators. GPR119 G protein-coupled receptor modulators are useful in treating, preventing, or slowing the progression of diseases requiring GPR119 G protein-coupled receptor modulator therapy. Thus, the disclosure also concerns compositions comprising these novel compounds and methods of treating diseases or conditions related to the activity of the GPR119 G protein-coupled receptor by using any of these novel compounds or a composition comprising any of such novel compounds.
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