Invention Grant
- Patent Title: Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
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Application No.: US14038304Application Date: 2013-09-26
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Publication No.: US09174982B2Publication Date: 2015-11-03
- Inventor: Milan Bruncko , Hong Ding , George A. Doherty , Steven W. Elmore , Lisa A. Hasvold , Laura Hexamer , Aaron R. Kunzer , Xiaohong Song , Andrew J. Souers , Gerard M. Sullivan , Zhi-Fu Tao , Gary T. Wang , Le Wang , Xilu Wang , Michael D. Wendt , Robert A. Mantei , Todd M. Hansen
- Applicant: AbbVie Inc. , Genentech, Inc. , The Walter and Eliza Hall Institute of Medical Research
- Applicant Address: US IL North Chicago US CA South San Francisco AU Parkville
- Assignee: ABBVIE INC.,GENENTECH, INC.,THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH
- Current Assignee: ABBVIE INC.,GENENTECH, INC.,THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH
- Current Assignee Address: US IL North Chicago US CA South San Francisco AU Parkville
- Agency: Jones Day
- Main IPC: C07D209/82
- IPC: C07D209/82 ; C07D403/12 ; C07D401/14 ; C07D471/04 ; C07D519/00 ; A61K31/496

Abstract:
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
Public/Granted literature
- US20140094471A1 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES Public/Granted day:2014-04-03
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