- 专利标题: Functional influenza virus-like particles (VLPs)
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申请号: US14149365申请日: 2014-01-07
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公开(公告)号: US09180180B2公开(公告)日: 2015-11-10
- 发明人: Gale Smith , Rick Bright , Peter Pushko , Jinyou Zhang , Kutub Mahmood
- 申请人: NOVAVAX, INC.
- 申请人地址: US MD Gaithersburg
- 专利权人: NOVAVAX, INC.
- 当前专利权人: NOVAVAX, INC.
- 当前专利权人地址: US MD Gaithersburg
- 代理机构: Cooley, LLP
- 代理商 Fraser D. Brown
- 主分类号: A61K39/145
- IPC分类号: A61K39/145 ; C07K14/005 ; C12N7/00 ; C12N15/86 ; A61K39/12 ; A61K39/00
摘要:
The present invention discloses and claims virus like particles (VLPs) that express and/or contains seasonal influenza virus proteins, avian influenza virus proteins and/or influenza virus proteins from viruses with pandemic potential. The invention includes vector constructs comprising said proteins, cells comprising said constructs, formulations and vaccines comprising VLPs of the inventions. The invention also includes methods of making and administrating VLPs to vertebrates, including methods of inducing substantial immunity to either seasonal and avian influenza, or at least one symptom thereof.
公开/授权文献
- US20140193447A1 FUNCTIONAL INFLUENZA VIRUS-LIKE PARTICLES (VLPS) 公开/授权日:2014-07-10
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