发明授权
- 专利标题: Epo knockout GFP anemic mouse
- 专利标题(中): Epo敲除GFP贫血小鼠
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申请号: US14008703申请日: 2012-03-29
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公开(公告)号: US09180207B2公开(公告)日: 2015-11-10
- 发明人: Masayuki Yamamoto , Naoko Minegishi , Shun Yamazaki
- 申请人: Masayuki Yamamoto , Naoko Minegishi , Shun Yamazaki
- 申请人地址: JP Miyagi
- 专利权人: TOHOKU TECHNO ARCH CO., LTD.
- 当前专利权人: TOHOKU TECHNO ARCH CO., LTD.
- 当前专利权人地址: JP Miyagi
- 代理机构: Pearne & Gordon LLP
- 优先权: JP2011-083664 20110405
- 国际申请: PCT/JP2012/002207 WO 20120329
- 国际公布: WO2012/137449 WO 20121011
- 主分类号: A01K67/027
- IPC分类号: A01K67/027 ; A01K67/033 ; A61K49/00 ; G01N33/50
摘要:
The present invention relates to a model animal spontaneously developing anemia. More specifically, the invention relates to a transgenic non-human mammal spontaneously developing anemia associated with a postnatal decrease in production of erythropoietin (Epo), Epo-producing cells prepared from the transgenic non-human mammal, and a screening method using the Epo-producing cells.
公开/授权文献
- US20140053288A1 EPO KNOCKOUT GFP ANEMIC MOUSE 公开/授权日:2014-02-20
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