发明授权
- 专利标题: Heteroaryl compounds as sodium channel blockers
- 专利标题(中): 杂芳基化合物作为钠通道阻断剂
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申请号: US14355554申请日: 2012-10-30
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公开(公告)号: US09181185B2公开(公告)日: 2015-11-10
- 发明人: Jiangchao Yao
- 申请人: Purdue Pharma L.P.
- 申请人地址: US CT Stamford
- 专利权人: Purdue Pharma L.P.
- 当前专利权人: Purdue Pharma L.P.
- 当前专利权人地址: US CT Stamford
- 代理机构: Purdue Pharma L.P.
- 代理商 Alan L. Koller; Weiyang Yang
- 国际申请: PCT/IB2012/002191 WO 20121030
- 国际公布: WO2013/064883 WO 20130510
- 主分类号: C07D213/00
- IPC分类号: C07D213/00 ; C07D401/04 ; C07D213/56 ; C07D401/12 ; C07D239/26 ; C07D213/57 ; C07D213/643 ; C07D213/65
摘要:
The invention relates to aryl substituted compounds of Formula (I): and pharmaceutically acceptable salts, prodrugs, or solvates thereof, wherein Het, G, A, R, and n are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula I to treat a disorder responsive to the blockade of sodium channels. Compounds of the present invention are especially useful for treating pain.
公开/授权文献
- US20140288092A1 HETEROARYL COMPOUNDS AS SODIUM CHANNEL BLOCKERS 公开/授权日:2014-09-25
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