- 专利标题： Aryl ureas as kinase inhibitors
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申请号： US13365687申请日： 2012-02-03
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公开(公告)号： US09181188B2公开(公告)日： 2015-11-10
- 发明人: Jacques Dumas , William J. Scott , Du-Schieng Chien , Ala Nassar , Wendy Lee , Susan Bjorge , Laszlo L. Musza , Bernd Riedl
- 申请人： Jacques Dumas , William J. Scott , Du-Schieng Chien , Ala Nassar , Wendy Lee , Susan Bjorge , Laszlo L. Musza , Bernd Riedl
- 申请人地址： US NJ Whippany
- 专利权人： Bayer Healthcare LLC
- 当前专利权人： Bayer Healthcare LLC
- 当前专利权人地址： US NJ Whippany
- 代理机构： Millen, White, Zelano & Branigan, P.C.
- 主分类号： C07D213/18
- IPC分类号： C07D213/18 ; C07D213/79 ; C07D213/81 ; C07D213/89
摘要：
This invention relates to new aryl ureas and methods for their synthesis. The inventive compounds are useful in the treatment of (i) raf mediated diseases, for example, cancer, (ii) p38 mediated diseases such as inflammation and osteoporosis, and (iii) VEGF mediated diseases such as angiogenesis disorders.
公开/授权文献
- US20120136157A1 ARYL UREAS AS KINASE INHIBITORS 公开/授权日：2012-05-31
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