Invention Grant
US09181203B2 Substituted pyrazino[2,3-d]isooxazoles as intermediates for the synthesis of substituted pyrazinecarbonitriles and substituted pyrazinecarboxamides
有权
取代的吡嗪并[2,3-d]异恶唑作为合成取代的吡嗪甲腈和取代的吡嗪甲酰胺的中间体
![Substituted pyrazino[2,3-d]isooxazoles as intermediates for the synthesis of substituted pyrazinecarbonitriles and substituted pyrazinecarboxamides](/docs/US/2015-11-10/US09181203B2/abs.jpg.600x600.jpg)
- Patent Title: Substituted pyrazino[2,3-d]isooxazoles as intermediates for the synthesis of substituted pyrazinecarbonitriles and substituted pyrazinecarboxamides
- Patent Title (中): 取代的吡嗪并[2,3-d]异恶唑作为合成取代的吡嗪甲腈和取代的吡嗪甲酰胺的中间体
-
Application No.: US14527174Application Date: 2014-10-29
-
Publication No.: US09181203B2Publication Date: 2015-11-10
- Inventor: Kouki Nakamura , Takeshi Murakami , Hiroyuki Naitou , Naoyuki Hanaki , Katsuyuki Watanabe
- Applicant: FUJIFILM Corporation , TOYAMA CHEMICAL CO., LTD.
- Applicant Address: JP Tokyo
- Assignee: FUJIFILM Corporation
- Current Assignee: FUJIFILM Corporation
- Current Assignee Address: JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JP2010-253414 20101112; JP2010-256510 20101117; JP2011-025760 20110209
- Main IPC: C07D241/18
- IPC: C07D241/18 ; C07D241/24 ; C07D261/18 ; C07D498/04 ; C07C239/18 ; C07C237/06 ; C07C251/38 ; C07C255/23 ; C07C255/29
![Substituted pyrazino[2,3-d]isooxazoles as intermediates for the synthesis of substituted pyrazinecarbonitriles and substituted pyrazinecarboxamides](/abs-image/US/2015/11/10/US09181203B2/abs.jpg.150x150.jpg)
Abstract:
The object of the present invention is to provide a compound which is useful as a production intermediate of pyrazine carboxamide derivative such as 6-fluoro-3-hydroxy-2-pyrazine carboxamide. The present invention provides a pyrazino[2,3-d]isoxazole derivative represented by the formula (I): wherein X represents a halogen atom, a hydroxyl group or a sulfamoyloxy group, and Y represents —C(═O)R or —CN; wherein R represents a hydrogen atom, an alkoxy group an aryloxy group, an alkyl group, an aryl group or an amino group.
Public/Granted literature
Information query
