Invention Grant
US09181344B2 Use of effector-function-deficient antibodies for treatment of auto-immune diseases
有权
使用效应子功能缺陷型抗体治疗自身免疫性疾病
- Patent Title: Use of effector-function-deficient antibodies for treatment of auto-immune diseases
- Patent Title (中): 使用效应子功能缺陷型抗体治疗自身免疫性疾病
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Application No.: US12096196Application Date: 2006-12-15
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Publication No.: US09181344B2Publication Date: 2015-11-10
- Inventor: Mario Losen , Pilar Martinez-Martinez , Marc H. De Baets , Yvo Graus , Janine Schuurman , Paul Parren
- Applicant: Mario Losen , Pilar Martinez-Martinez , Marc H. De Baets , Yvo Graus , Janine Schuurman , Paul Parren
- Applicant Address: DK Copenhagen
- Assignee: GENMAB A/S
- Current Assignee: GENMAB A/S
- Current Assignee Address: DK Copenhagen
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Jane E. Remillard, Esq.; Christopher L. Frank
- Priority: DK200600744 20060531
- International Application: PCT/DK2006/000719 WO 20061215
- International Announcement: WO2007/068255 WO 20070621
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/00
Abstract:
The invention relates to the treatment of autoimmune diseases and disorders, in particular myasthenia gravis, by administration of effector-function-deficient antibodies, wherein said effector-function-deficient antibodies are capable of competing with one or more of the auto-antibodies involved in mediating the antibody-mediated auto-immune disease or disorder for binding to a target auto-antigen.
Public/Granted literature
- US20090317382A1 USE OF EFFECTOR-FUNCTION-DEFICIENT ANTIBODIES FOR TREATMENT OF AUTO-IMMUNE DISEASES Public/Granted day:2009-12-24
Information query
