发明授权
- 专利标题: Methods and devices for in situ nucleic acid synthesis
- 专利标题(中): 用于原位核酸合成的方法和装置
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申请号: US13700291申请日: 2011-05-26
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公开(公告)号: US09187777B2公开(公告)日: 2015-11-17
- 发明人: Joseph Jacobson , Senthil Ramu , Daniel Schindler
- 申请人: Joseph Jacobson , Senthil Ramu , Daniel Schindler
- 申请人地址: US MA Cambridge
- 专利权人: Gen9, Inc.
- 当前专利权人: Gen9, Inc.
- 当前专利权人地址: US MA Cambridge
- 代理机构: Greenberg Traurig, LLP
- 代理商 Natalie Salem; Fang Xie
- 国际申请: PCT/US2011/038079 WO 20110526
- 国际公布: WO2011/150168 WO 20111201
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; C12P19/34 ; C12N15/10 ; C12N15/66
摘要:
Disclosed are compositions, methods and devices for the in situ synthesis of nucleic acids. In an exemplary embodiment, a support-bound oligonucleotide is elongated by addition of one or more nucleotides by hybridization of a partially double-stranded oligonucleotide, ligation and removal of unwanted nucleotides.
公开/授权文献
- US20130309725A1 Methods and Devices for In Situ Nucleic Acid Synthesis 公开/授权日:2013-11-21
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