发明授权
US09188595B2 Alzheimer's disease diagnosis based on mitogen-activated protein kinase phosphorylation
有权
基于丝裂原活化蛋白激酶磷酸化的阿尔茨海默病诊断
- 专利标题: Alzheimer's disease diagnosis based on mitogen-activated protein kinase phosphorylation
- 专利标题(中): 基于丝裂原活化蛋白激酶磷酸化的阿尔茨海默病诊断
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申请号: US12729042申请日: 2010-03-22
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公开(公告)号: US09188595B2公开(公告)日: 2015-11-17
- 发明人: Wei-Qin Zhao , Daniel L. Alkon
- 申请人: Wei-Qin Zhao , Daniel L. Alkon
- 申请人地址: US WV Morgantown
- 专利权人: Blanchett Rockefeller Neurosciences Institute
- 当前专利权人: Blanchett Rockefeller Neurosciences Institute
- 当前专利权人地址: US WV Morgantown
- 代理机构: Finnegan, Henderson, Farabow, Garrett & Dunner LLP
- 主分类号: G01N33/68
- IPC分类号: G01N33/68
摘要:
A method of diagnosing Alzheimer's disease in a patient comprises determining whether the phosphorylation level of an indicator protein in cells of the patient after stimulus with an activator compound is abnormally elevated as compared to a basal phosphorylation level, the indicator protein being e.g. Erk1/2 and the activator compound being e.g. bradykinin.
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