Embodiments of the present invention provide a wear-leveling method, a storage device, and an information system, where a storage region is divided into a plurality of storage sub-regions of the same size. The method includes: recording the accumulated number of write operations of each storage sub-region; and when the accumulated number of write operations of any one storage sub-region of the plurality of storage sub-regions reaches a predetermined remapping rate, mapping a logical address of the storage sub-region to a remapping physical address. With the wear-leveling method, the storage device, and the information system in the embodiments of the present invention, a logical address of a local data block on which too many write operations are performed may be evenly mapped to an overall physical storage region, thereby avoiding that local data is too hot and prolonging a service life of a storage medium.