Invention Grant
- Patent Title: Apoptosis inducing compounds
- Patent Title (中): 凋亡诱导化合物
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Application No.: US14349529Application Date: 2012-10-04
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Publication No.: US09193699B2Publication Date: 2015-11-24
- Inventor: Marc Lopez , Yves Collette , Lynda Mezil , Jean-Michel Brunel , Sebastien Combes
- Applicant: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) , UNIVERSITE D'AIX-MARSEILLE , L'INSTITUT PAOLI CALMETTE
- Applicant Address: FR Paris FR Paris FR Marseilles FR Marseilles
- Assignee: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.),UNIVERSITÉ D'AIX-MARSEILLE,L'INSTITUT PAOLI-CALMETTES
- Current Assignee: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.),UNIVERSITÉ D'AIX-MARSEILLE,L'INSTITUT PAOLI-CALMETTES
- Current Assignee Address: FR Paris FR Paris FR Marseilles FR Marseilles
- Agency: Whitham, Curtis, Christofferson & Cook, P.C.
- Priority: EP11306286 20111004
- International Application: PCT/EP2012/069629 WO 20121004
- International Announcement: WO2013/050476 WO 20130411
- Main IPC: C07D279/12
- IPC: C07D279/12
Abstract:
Provided are compounds of formula (I): wherein R1, R2, R3, R4 and R5 are independently selected from the group comprising, inter aliae, H, optionally substituted, branched or linear C1-C12 alkyl, halogen atom and C1-C12 haloalkyl, and wherein A represents a single bond or an optionally substituted C1-C6 alkylene radical, notably useful for the treatment of human cancers.
Public/Granted literature
- US20140296227A1 APOPTOSIS INDUCING COMPOUNDS Public/Granted day:2014-10-02
Information query
