发明授权
- 专利标题： Mineralocorticoid receptor antagonists
- 专利标题（中）： 盐皮质激素受体拮抗剂
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申请号： US14350888申请日： 2012-10-08
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公开(公告)号： US09193717B2公开(公告)日： 2015-11-24
- 发明人: Hong Shen , Christine Yang , Jason M. Cox , Kun Liu
- 申请人： Hong Shen , Christine Yang , Jason M. Cox , Kun Liu
- 申请人地址： US NJ Rahway
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway
- 代理商 Patricia A. Shatynski; Catherine D. Fitch
- 国际申请： PCT/US2012/059168 WO 20121008
- 国际公布： WO2013/055607 WO 20130418
- 主分类号： C07D413/04
- IPC分类号： C07D413/04 ; C07D413/14 ; C07D403/04 ; A61K31/422 ; A61K31/4439 ; A61K31/506 ; A61K31/5377
摘要：
The present invention is directed to compounds of the Formula (I) as well as pharmaceutically acceptable salts thereof, that are aldosterone receptor antagonists which might be useful for treating aldosterone-mediated diseases. The invention furthermore relates to processes for preparing compounds of the Formula (I), to their possible use for the treatment of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical compositions which comprise compounds of the Formula (I).
公开/授权文献
- US20140256723A1 MINERALOCORTICOID RECEPTOR ANTAGONISTS 公开/授权日：2014-09-11