Invention Grant
US09193770B2 Immunogenic compositions containing Escherichia coli H7 flagella and methods of use thereof
有权
含有大肠杆菌H7鞭毛的免疫原性组合物及其使用方法
- Patent Title: Immunogenic compositions containing Escherichia coli H7 flagella and methods of use thereof
- Patent Title (中): 含有大肠杆菌H7鞭毛的免疫原性组合物及其使用方法
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Application No.: US12738627Application Date: 2008-10-17
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Publication No.: US09193770B2Publication Date: 2015-11-24
- Inventor: David Gally , Tom Nathan McNeilly , David George Emslie Smith , Chris Low , Arvind Kumar Mahajan , Stuart W. Naylor
- Applicant: David Gally , Tom Nathan McNeilly , David George Emslie Smith , Chris Low , Arvind Kumar Mahajan , Stuart W. Naylor
- Applicant Address: GB Edinburgh GB Penicuik GB Edinburgh
- Assignee: THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH,MOREDUN RESEARCH INSTITUTE,THE SCOTTISH AGRICULTURAL COLLEGE
- Current Assignee: THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH,MOREDUN RESEARCH INSTITUTE,THE SCOTTISH AGRICULTURAL COLLEGE
- Current Assignee Address: GB Edinburgh GB Penicuik GB Edinburgh
- Agency: Foley & Lardner LLP
- Agent Gilberto M. Villacorta; Tianran Yan
- Priority: GB0720250.0 20071017
- International Application: PCT/GB2008/003515 WO 20081017
- International Announcement: WO2009/050474 WO 20090423
- Main IPC: A61K39/00
- IPC: A61K39/00 ; C07K14/245 ; A61K39/108 ; C07K16/12

Abstract:
Immunogenic compositions containing Escherichia coli O157:H7 flagella including fusion proteins and methods using the immunogenic compositions are disclosed. Inducing an immune response in an animal to Escherichia coli O157:H7 flagella will result in prevention of colonization by Escherichia coli O157:H7 in the animal or a reduction in the amount of Escherichia coli O157:H7 infecting the animal. The immune composition will prevent or reduce the attachment of Escherichia coli O157:H7 to cells within the animal.
Public/Granted literature
- US20110008379A1 IMMUNOGENIC COMPOSITIONS CONTAINING ESCHERICHIA COLI H7 FLAGELLA AND METHODS OF USE THEREOF Public/Granted day:2011-01-13
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