发明授权
US09198902B2 1,4-dihydropyridine-3,5-dicarboxylate derivatives and preparation and use thereof
有权
1,4-二氢吡啶-3,5-二羧酸酯衍生物及其制备和用途
- 专利标题： 1,4-dihydropyridine-3,5-dicarboxylate derivatives and preparation and use thereof
- 专利标题（中）： 1,4-二氢吡啶-3,5-二羧酸酯衍生物及其制备和用途
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申请号： US14114346申请日： 2012-05-02
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公开(公告)号： US09198902B2公开(公告)日： 2015-12-01
- 发明人: Hui Zhang , Mingwei Fan , Liang Sun
- 申请人： Hui Zhang , Mingwei Fan , Liang Sun
- 申请人地址： CN Jinan, Shandong Province
- 专利权人： Xuanzhu Pharma Co., Ltd.
- 当前专利权人： Xuanzhu Pharma Co., Ltd.
- 当前专利权人地址： CN Jinan, Shandong Province
- 代理机构： Kilpatrick Townsend & Stockton LLP
- 优先权： CN201110109496 20110429
- 国际申请： PCT/CN2012/000577 WO 20120502
- 国际公布： WO2012/146067 WO 20121101
- 主分类号： C07D401/14
- IPC分类号： C07D401/14 ; C07D401/12 ; C07D417/14 ; A61K31/4439 ; A61K31/444 ; A61K45/06 ; A61K31/44
摘要：
The present invention relates to a 1,4-dihydropyridine-3,5-dicarboxylate compound of general compound (I), a process for preparing the same, a use thereof for the manufacture of a medicament for treating and/or preventing kidney injury, cardiovascular diseases and/or endocrine diseases, as well as a pharmaceutical composition and a pharmaceutical formulation containing said compounds, wherein the definitions of R1, R2, R3, R4, R5, R6, R7, R8, m, n1, n2, p and q are the same as those defined in the description.
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