发明授权
- 专利标题： Compounds and compositions as C-kit kinase inhibitors
- 专利标题（中）： 化合物和组合物作为C-kit激酶抑制剂
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申请号： US13595575申请日： 2012-08-27
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公开(公告)号： US09199981B2公开(公告)日： 2015-12-01
- 发明人: Vince Yeh , Xiaolin Li , Xiaodong Liu , Jon Loren , Valentina Molteni , Juliet Nabakka , Bao Nguyen , Hank Michael James Petrassi
- 申请人： Vince Yeh , Xiaolin Li , Xiaodong Liu , Jon Loren , Valentina Molteni , Juliet Nabakka , Bao Nguyen , Hank Michael James Petrassi
- 申请人地址： CH Basel
- 专利权人： NOVARTIS AG
- 当前专利权人： NOVARTIS AG
- 当前专利权人地址： CH Basel
- 代理机构： The Genomics Institute of the Novartis Research Foundation
- 代理商 Daniel E. Raymond
- 主分类号： C07D401/02
- IPC分类号： C07D401/02 ; C07D401/10 ; A61K31/437 ; A61K31/4353 ; C07D471/04
摘要：
The invention provides compounds and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of c-kit or c-kit and PDGFR (PDGFRα, PDGFRβ) kinases.
公开/授权文献
- US20130059846A1 COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS 公开/授权日：2013-03-07