发明授权
US09199983B2 3-aryl-6-aryl-[1,2,4]triazolo[4,3-α]pyridines as inhibitors of cell proliferation and the use thereof
有权
3-芳基-6-芳基 - [1,2,4]三唑并[4,3-α]吡啶作为细胞增殖抑制剂及其用途
![3-aryl-6-aryl-[1,2,4]triazolo[4,3-α]pyridines as inhibitors of cell proliferation and the use thereof](/docs/US/2015-12-01/US09199983B2/abs.jpg.600x600.jpg)
- 专利标题： 3-aryl-6-aryl-[1,2,4]triazolo[4,3-α]pyridines as inhibitors of cell proliferation and the use thereof
- 专利标题（中）： 3-芳基-6-芳基 - [1,2,4]三唑并[4,3-α]吡啶作为细胞增殖抑制剂及其用途
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申请号： US13885896申请日： 2011-11-16
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公开(公告)号： US09199983B2公开(公告)日： 2015-12-01
- 发明人: Suixiong Cai , Ye Edward Tian , Haijun Dong , Lei Chen , Zenghui Yu , Feng Yin , Sheng Bi , Lijun Liu , Lizhen Wu
- 申请人： Suixiong Cai , Ye Edward Tian , Haijun Dong , Lei Chen , Zenghui Yu , Feng Yin , Sheng Bi , Lijun Liu , Lizhen Wu
- 代理机构： Sterne, Kessler, Goldstein & Fox P.L.L.C.
- 优先权： WOPCT/CN2010/078761 20101116
- 国际申请： PCT/CN2011/082264 WO 20111116
- 国际公布： WO2012/065546 WO 20120524
- 主分类号： C07D401/14
- IPC分类号： C07D401/14 ; A61K31/437 ; C07D471/04 ; A61K31/444 ; A61K31/506 ; A61K45/06 ; A61N5/10
![3-aryl-6-aryl-[1,2,4]triazolo[4,3-α]pyridines as inhibitors of cell proliferation and the use thereof](/abs-image/US/2015/12/01/US09199983B2/abs.jpg.150x150.jpg)
摘要：
Disclosed are 3-aryl-6-aryl-[1,2,4]triazolo[4,3-a]pyridines thereof, represented by the Formula (I) wherein Ar1, Ar2, R1-R3 are defined herein. Compounds having Formula (I) are inhibitors of cell proliferation. Therefore, compounds of the invention may be used to treat clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.
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