Invention Grant
US09200273B2 Fibronectin type III repeat based protein scaffolds with alternative binding surfaces
有权
具有替代结合表面的纤连蛋白III型重复基于蛋白质支架
- Patent Title: Fibronectin type III repeat based protein scaffolds with alternative binding surfaces
- Patent Title (中): 具有替代结合表面的纤连蛋白III型重复基于蛋白质支架
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Application No.: US13628393Application Date: 2012-09-27
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Publication No.: US09200273B2Publication Date: 2015-12-01
- Inventor: Michael Diem , Steven Jacobs
- Applicant: Michael Diem , Steven Jacobs
- Applicant Address: US PA Horsham
- Assignee: Janssen Biotech, Inc.
- Current Assignee: Janssen Biotech, Inc.
- Current Assignee Address: US PA Horsham
- Agent Eric Dichter
- Main IPC: C40B50/06
- IPC: C40B50/06 ; C12N15/10 ; C40B40/08
Abstract:
Protein scaffolds and scaffold libraries based on a fibronectin type III (FN3) repeat with an alternative binding surface design, isolated nucleic acids encoding the protein scaffolds, vectors, host cells, and methods of making thereof are useful in the generation of therapeutic molecules and treatment and diagnosis of diseases and disorders.
Public/Granted literature
- US20130079243A1 Fibronectin Type III Repeat Based Protein Scaffolds with Alternative Binding Surfaces Public/Granted day:2013-03-28
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