发明授权
US09211342B2 Stable growth hormone compounds resistant to proteolytic degradation
有权
稳定的生长激素化合物抗蛋白水解降解
- 专利标题: Stable growth hormone compounds resistant to proteolytic degradation
- 专利标题(中): 稳定的生长激素化合物抗蛋白水解降解
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申请号: US13574128申请日: 2011-01-24
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公开(公告)号: US09211342B2公开(公告)日: 2015-12-15
- 发明人: Helle Demuth , Christine Brunn Schioedt , Leif Noerskov-Lauritsen , Jianhe Chen , Peter Thygesen
- 申请人: Helle Demuth , Christine Brunn Schioedt , Leif Noerskov-Lauritsen , Jianhe Chen , Peter Thygesen
- 申请人地址: CH Zurich
- 专利权人: NOVO NORDISK HEALTHCARE AG
- 当前专利权人: NOVO NORDISK HEALTHCARE AG
- 当前专利权人地址: CH Zurich
- 代理商 Jianjie Hu
- 优先权: EP10151405 20100122; WOPCT/CN2010/001120 20100723
- 国际申请: PCT/EP2011/050909 WO 20110124
- 国际公布: WO2011/089250 WO 20110728
- 主分类号: A61K38/27
- IPC分类号: A61K38/27 ; C07K14/61 ; A61K47/48 ; A61K38/00
摘要:
The present invention relates to growth hormone (GH) compounds having additional disulphide bridges and at least one additional single point mutation making the compounds resistant to proteolytic degradation.
公开/授权文献
- US20130040883A1 STABLE GROWTH HORMONE COMPOUNDS 公开/授权日:2013-02-14
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