Invention Grant
US09213032B2 Use of LRIG1 as a biomarker for identifying a subject for application of anti-c-Met antibodies
有权
使用LRIG1作为鉴定受试者应用抗c-Met抗体的生物标志物
- Patent Title: Use of LRIG1 as a biomarker for identifying a subject for application of anti-c-Met antibodies
- Patent Title (中): 使用LRIG1作为鉴定受试者应用抗c-Met抗体的生物标志物
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Application No.: US13949041Application Date: 2013-07-23
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Publication No.: US09213032B2Publication Date: 2015-12-15
- Inventor: Ji Min Lee , Kyung Ah Kim , Bo Gyou Kim
- Applicant: SAMSUNG ELECTRONICS CO., LTD.
- Applicant Address: KR Suwon-Si
- Assignee: SAMSUNG ELECTRONICS CO., LTD.
- Current Assignee: SAMSUNG ELECTRONICS CO., LTD.
- Current Assignee Address: KR Suwon-Si
- Agency: Leydig, Voit & Mayer, Ltd.
- Priority: KR10-2012-0080144 20120723; KR10-2012-0102398 20120914
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/574 ; C12Q1/68 ; C07K16/30 ; C07K16/28 ; A61K39/00
Abstract:
A method of identifying a cell sample or subject suitable for treatment with an anti-c-Met antibody or antigen-binding fragment thereof that specifically binds to an epitope within a SEMA domain of a c-Met protein by determining the presence of LRIG1 in a cell sample from the subject, as well as related methods and compositions.
Public/Granted literature
- US20140105902A1 USE OF LRIG1 AS A BIOMARKER FOR IDENTIFYING A SUBJECT FOR APPLICATION OF ANTI-C-MET ANTIBODIES Public/Granted day:2014-04-17
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