Systems and methods for obfuscating user data in a remote web-based application are disclosed. According to one method, user inputs to a displayed web page of the remote web-based application are received at a first web browser that is used by the user, wherein at least a portion of the user inputs comprise user-inputted data intended to be stored at the web-based application. The user inputs are transmitted to a management component that is configured to interact with a second web browser that communicates with the web-based application. The management component obfuscates at least a portion of the user-inputted data and forwards the obfuscated and un-obfuscated portions of the user inputs to the second web browser, which correspondingly transmits the obfuscated and un-obfuscated portions of the user inputs to the remote web-based application.