A method and device for reporting antenna calibration information and determining antenna calibration factor are provided by the present invention. When reporting the antenna calibration information, a user equipment (UE) estimates the downlink equivalent baseband channel from a plurality of antennas of the base station to the UE; according to the equivalent baseband channel, determines the amplitude response and delay value to be reported, and then reports the amplitude response and delay value to the base station. When determining the antenna calibration factor, according to the uplink signal sent by the UE on the base station-directed time-frequency resources, the base station determines the amplitude response and the delay value; according to the amplitude response and delay value reported by the UE and according to the amplitude response and delay value determined by the uplink signal, the base station calculates the antenna calibration factor. Because the UE pre-processing process is added, the sensitivity degrees to the channel estimation error and to the channel Doppler extension are reduced.