发明授权
- 专利标题： Cyclic amine substituted oxazolidinone CETP inhibitor
- 专利标题（中）： 环胺取代的恶唑烷酮CETP抑制剂
-
申请号： US13881896申请日： 2011-10-25
-
公开(公告)号： US09221834B2公开(公告)日： 2015-12-29
- 发明人: Zhijian Lu , Yi-Heng Chen , Cameron Smith , Hong Li , Christopher F. Thompson , Julianne Hunt , Florida Kallashi , Ramzi Sweis , Peter Sinclair , Samantha E. Adamson , Guizhen Dong , Debra L. Ondeyka , Xiaoxia Qian , Wanying Sun , Petr Vachal , Kake Zhao
- 申请人： Zhijian Lu , Yi-Heng Chen , Cameron Smith , Hong Li , Christopher F. Thompson , Julianne Hunt , Florida Kallashi , Ramzi Sweis , Peter Sinclair , Samantha E. Adamson , Guizhen Dong , Debra L. Ondeyka , Xiaoxia Qian , Wanying Sun , Petr Vachal , Kake Zhao
- 申请人地址： US NJ Rahway
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway
- 代理商 Eric A. Meade; Catherine D. Fitch
- 国际申请： PCT/US2011/057584 WO 20111025
- 国际公布： WO2012/058187 WO 20120503
- 主分类号： A61K31/4439
- IPC分类号： A61K31/4439 ; A61K31/506 ; A61K31/5377 ; A61K31/4545 ; A61K31/497 ; A61K31/444 ; C07D491/08 ; C07D417/14 ; C07D413/14 ; A61K31/42 ; A61K45/06 ; C07D413/06
摘要：
Compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compound of Formula I, A3 is a substituted phenyl group or indanyl group. Formula (I).
公开/授权文献
- US20130331372A1 Cyclic Amine Substituted Oxazolidinone CETP Inhibitor 公开/授权日：2013-12-12
信息查询
IPC分类:
