An apparatus and method for supporting a location update registration process used for an idle mode operation of a Mobile Station (MS) in a Machine-to-Machine (M2M) communication are provided. The method includes determining whether a system global location update registration timer is applied to the MS, when it is determined that the global location update registration timer is not applied, determining a timer for updating a location when the MS operates in an idle mode, and transmitting a message including the timer to the MS.