Invention Grant
US09238666B2 Phosphoramidic acid prodrugs of 5-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl] pyridine-3-sulfonamide
有权
5- [5-苯基-4-（吡啶-2-基甲基氨基）喹唑啉-2-基]吡啶-3-磺酰胺的磷酰胺酸前药
![Phosphoramidic acid prodrugs of 5-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl] pyridine-3-sulfonamide](/docs/US/2016-01-19/US09238666B2/abs.jpg.600x600.jpg)
- Patent Title: Phosphoramidic acid prodrugs of 5-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl] pyridine-3-sulfonamide
- Patent Title (中): 5- [5-苯基-4-（吡啶-2-基甲基氨基）喹唑啉-2-基]吡啶-3-磺酰胺的磷酰胺酸前药
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Application No.: US14406543Application Date: 2013-06-10
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Publication No.: US09238666B2Publication Date: 2016-01-19
- Inventor: Jayakumar S. Warrier , Navnath Dnyanoba Yadav
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Mary K. VanAtten
- International Application: PCT/US2013/044882 WO 20130610
- International Announcement: WO2013/188254 WO 20131219
- Main IPC: C07F9/6512
- IPC: C07F9/6512 ; C07D401/14 ; C07F9/6558 ; A61K31/675
![Phosphoramidic acid prodrugs of 5-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl] pyridine-3-sulfonamide](/abs-image/US/2016/01/19/US09238666B2/abs.jpg.150x150.jpg)
Abstract:
A compound of structural formula (I), wherein R is H or —PO3H or a pharmaceutically acceptable salt form thereof. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
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