Invention Grant
- Patent Title: Substituted benzoazepines as toll-like receptor modulators
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Application No.: US14016951Application Date: 2013-09-03
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Publication No.: US09242964B2Publication Date: 2016-01-26
- Inventor: James Jeffry Howbert , Gregory Dietsch , Robert M. Hershberg , Laurence E. Burgess , George A. Doherty , C. Todd Eary , Robert D. Groneberg , Zachary Jones
- Applicant: VentiRx Pharmaceuticals, Inc. , Array BioPharma, Inc.
- Applicant Address: US CA San Diego US CO Boulder
- Assignee: VENTIRX PHARMACEUTICALS, INC.,ARRAY BIOPHARMA, INC.
- Current Assignee: VENTIRX PHARMACEUTICALS, INC.,ARRAY BIOPHARMA, INC.
- Current Assignee Address: US CA San Diego US CO Boulder
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: A61K31/55
- IPC: A61K31/55 ; C07D223/16 ; C07D403/14 ; A61K31/4025 ; C07D401/04 ; C07D403/04 ; C07D403/10 ; C07D401/14
Abstract:
Provided are compositions and methods useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The compositions and methods have use in treating or preventing disease, including cancer, autoimmune disease, infectious disease, inflammatory disorder, graft rejection, and graft-verses-host disease.
Public/Granted literature
- US20140142086A1 Substituted Benzoazepines as Toll-Like Receptor Modulators Public/Granted day:2014-05-22
Information query
