Invention Grant
US09255141B2 Multimeric IL-15 soluble fusion molecules and methods of treating neoplasia and HIV using same
有权
多聚IL-15可溶性融合分子和使用其治疗瘤形成和HIV的方法
- Patent Title: Multimeric IL-15 soluble fusion molecules and methods of treating neoplasia and HIV using same
- Patent Title (中): 多聚IL-15可溶性融合分子和使用其治疗瘤形成和HIV的方法
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Application No.: US13769179Application Date: 2013-02-15
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Publication No.: US09255141B2Publication Date: 2016-02-09
- Inventor: Hing C. Wong , Peter Rhode , Bai Liu , Xiaoyun Zhu , Kai-ping Han
- Applicant: Hing C. Wong , Peter Rhode , Bai Liu , Xiaoyun Zhu , Kai-ping Han
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent Peter F. Corless, Esq.; Daniel W. Clarke
- Main IPC: C07K16/18
- IPC: C07K16/18 ; C07K14/54 ; C07K14/715 ; A61K38/20 ; C07K16/28 ; A61K45/06 ; A61K38/17
Abstract:
The present invention features compositions and methods featuring ALT-803, a complex of an interleukin-15 (IL-15) superagonist mutant and a dimeric IL-15 receptor α/Fc fusion protein useful for enhancing an immune response against a neoplasia (e.g., multiple myeloma, melanoma, lymphoma) or a viral infection (e.g., human immunodeficiency virus).
Public/Granted literature
- US20140242025A1 MULTIMERIC IL-15 SOLUBLE FUSION MOLECULES AND METHODS OF MAKING AND USING SAME Public/Granted day:2014-08-28
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