Invention Grant
- Patent Title: Exosomes and diagnostic biomarkers
- Patent Title (中): 外来体和诊断生物标志物
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Application No.: US14052378Application Date: 2013-10-11
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Publication No.: US09255924B2Publication Date: 2016-02-09
- Inventor: Jeffrey S. Schorey , Karen M. Dobos
- Applicant: University of Notre Dame du Lac , Colorado State University Research Foundation
- Applicant Address: US IN Notre Dame US CO Fort Collins
- Assignee: University of Notre Dame du Lac,Colorado State University Research Foundation
- Current Assignee: University of Notre Dame du Lac,Colorado State University Research Foundation
- Current Assignee Address: US IN Notre Dame US CO Fort Collins
- Agency: Haukaas Fortius PLLC
- Agent Michael H. Haukaas
- Main IPC: A61K39/04
- IPC: A61K39/04 ; C12N1/20 ; G01N33/569 ; G01N33/68 ; C07K14/35
Abstract:
The invention provides methods for the detection of M. tuberculosis proteins in or on exosomes derived from infected individuals. The methods can use a proteomic approach including mass spectroscopy, data mining and multiplex reaction monitoring to quickly examine a large amount of M. tuberculosis proteins to determine the best biomarkers for use in diagnostic tests to identify active TB patients.
Public/Granted literature
- US20140113305A1 EXOSOMES AND DIAGNOSTIC BIOMARKERS Public/Granted day:2014-04-24
Information query
