This disclosure describes techniques for selectively activating a resume check operation in a single instruction, multiple data (SIMD) processing system. A processor is described that is configured to selectively enable or disable a resume check operation for a particular instruction based on information included in the instruction that indicates whether a resume check operation is to be performed for the instruction. A compiler is also described that is configured to generate compiled code which, when executed, causes a resume check operation to be selectively enabled or disabled for particular instructions. The compiled code may include one or more instructions that each specify whether a resume check operation is to be performed for the respective instruction. The techniques of this disclosure may be used to reduce the power consumption of and/or improve the performance of a SIMD system that utilizes a resume check operation to manage the reactivation of deactivated threads.