Mechanisms are provided to implement framework level mode specific file access operations. In a mode such as a work or enterprise mode, read and write accesses are directed to one or more secured locations. File data and metadata may be secured with encryption and/or authentication mechanisms. Conventional mobile solutions provide only for mode encryption distinctions at the application level, e.g. one work application may prevent access to certain data, but a different application may want to allow access to that same data. Various embodiments provide framework level mode sensitive encryption that does not require different, mutually exclusive, or possibly conflicting applications or platforms. A device and associated applications may have access to different data based on a current mode.