- Patent Title: Conjugates of polymers having a therapeutically active agent and an angiogenesis targeting moiety attached thereto and uses thereof in the treatment of angiogenesis related diseases
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Application No.: US14082224Application Date: 2013-11-18
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Publication No.: US09259482B2Publication Date: 2016-02-16
- Inventor: Ronit Satchi-Fainaro , Maria Jesus Vicent Docon
- Applicant: Ramot at Tel-Aviv University Ltd. , Fundacion de la Comunidad Valenciana Centro de Investigacion Principe Felipe
- Applicant Address: IL Tel-Aviv ES Valencia
- Assignee: Ramot at Tel-Aviv University Ltd.,Fundacion de la Comunidad Valenciana Centro de Investigacion Principe Felipe
- Current Assignee: Ramot at Tel-Aviv University Ltd.,Fundacion de la Comunidad Valenciana Centro de Investigacion Principe Felipe
- Current Assignee Address: IL Tel-Aviv ES Valencia
- Main IPC: A61K31/74
- IPC: A61K31/74 ; A61K47/48 ; A61K31/336 ; A61K31/337 ; G01N33/68 ; A61K49/00
Abstract:
Conjugates of a polymer having attached thereto an angiogenesis targeting moiety and a therapeutically active agent such as an anti-cancer agent or anti-angiogenesis agent, and processes of preparing same are disclosed.Pharmaceutical compositions containing these conjugates and uses thereof in the treatment of angiogenesis-related medical conditions such as cancer and cancer metastases are also disclosed.
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