A three-dimensional shape measurement system includes a three-dimensional shape measuring machine that outputs spatial coordinate data on a probe for measuring a work, and a control PC that processes the spatial coordinate data. The three-dimensional shape measurement machine includes a plurality of articulated-armed three-dimensional shape measuring machines that are arranged so that measurement ranges of the probes overlap each other to allow measurement of part or all of the work, and configured such that each can output spatial coordinate data. The control PC includes a coordinate data pool that retains the spatial coordinate data in an identifiable manner with respect to each of the three-dimensional shape measuring machines, and a synthesis unit that synthesizes the spatial coordinate data retained in the coordinate data pool.