Disclosed is a method for removing signal interference in a MIMO-based interference removing apparatus including transmitting a reference signal to at least one receiver; if channel information is estimated by the receiver, receiving the estimated channel information from the receiver as a feedback signal; and producing transmission pre-coding matrix, beam forming matrix, and weighted matrix using the received channel information. Further, the method includes transmitting information containing the transmission pre-coding matrix, the beam forming matrix, and the weighted matrix by including them in a pilot signal to the receiver, and the MIMO-based interference removing apparatus comprises at least one transmitter.