Invention Grant
- Patent Title: Phthalazinone ketone derivative, preparation method thereof, and pharmaceutical use thereof
- Patent Title (中): 酞嗪酮衍生物及其制备方法及其药物用途
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Application No.: US13811957Application Date: 2011-07-26
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Publication No.: US09273052B2Publication Date: 2016-03-01
- Inventor: Peng Cho Tang , Xin Li , Xiangqin Li , Yang Chen , Bin Wang , Zhe Zhu
- Applicant: Peng Cho Tang , Xin Li , Xiangqin Li , Yang Chen , Bin Wang , Zhe Zhu
- Applicant Address: CN Lianyungang, Jiangsu
- Assignee: Jiangsu Hansoh Pharmaceutical Co., Ltd.
- Current Assignee: Jiangsu Hansoh Pharmaceutical Co., Ltd.
- Current Assignee Address: CN Lianyungang, Jiangsu
- Agency: Panitch Schwarze Belisario & Nadel LLP
- Priority: CN201010248307 20100809
- International Application: PCT/CN2011/001223 WO 20110726
- International Announcement: WO2012/019427 WO 20120216
- Main IPC: A61K31/495
- IPC: A61K31/495 ; C07D487/04 ; A61K31/502 ; A61K45/00 ; A61K31/4188

Abstract:
A phthalazinone ketone derivative as represented by formula (I), a preparation method thereof, a pharmaceutical composition containing the derivative, a use thereof as a poly (ADP-ribose) polymerase (PARP) inhibitor, and a cancer treatment method thereof are described.
Public/Granted literature
- US20130131068A1 PHTHALAZINONE KETONE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL USE THEREOF Public/Granted day:2013-05-23
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