Invention Grant
US09273058B2 Substituted pyrazolo-piperazines as casein kinase 1 δ/ε inhibitors
有权
取代的吡唑并 - 哌嗪作为酪蛋白激酶1δ/ 抑制剂
- Patent Title: Substituted pyrazolo-piperazines as casein kinase 1 δ/ε inhibitors
- Patent Title (中): 取代的吡唑并 - 哌嗪作为酪蛋白激酶1δ/ 抑制剂
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Application No.: US14541343Application Date: 2014-11-14
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Publication No.: US09273058B2Publication Date: 2016-03-01
- Inventor: Upender Velaparthi , Chetan Padmakar Darne , Peiying Liu , Mark D. Wittman , Bradley C. Pearce , Erika M. V. Araujo , Bireshwar Dasgupta , Jalathi Surendran Nair , Sakthi Kumaran Janakiraman , Chandrasekhar Reddy Rachamreddy , Mettu Mallikarjuna Rao , Arul Mozhi Selvan Subbiah Karuppiah , Bandreddy Subba Reddy , Pulicharla Nagalakshmi , Rajesh Onkardas Bora , Shilpa Holehatti Maheshwarappa , Selvakumar Kumaravel , Dibakar Mullick , Ramesh Sistla
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Hong Liu
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D487/10 ; C07D487/20 ; C07D491/147 ; C07D491/20 ; A61K31/4985 ; A61K31/499 ; A61K31/501 ; A61K31/506 ; A61K31/5377 ; A61P19/02
Abstract:
The invention provides compounds of Formula (I): and pharmaceutically acceptable salts thereof. The compounds of Formula (I) inhibit protein kinase activity thereby making them useful as anticancer agents.
Public/Granted literature
- US20150133428A1 NOVEL SUBSTITUTED PYRAZOLO-PIPERAZINES AS CASEIN KINASE 1 D/E INHIBITORS Public/Granted day:2015-05-14
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