Invention Grant
- Patent Title: FGF mutants with reduced proteolysis and aggregation
- Patent Title (中): 具有降低的蛋白水解和聚集的FGF突变体
-
Application No.: US14134482Application Date: 2013-12-19
-
Publication No.: US09273106B2Publication Date: 2016-03-01
- Inventor: Edward John Belouski , Murielle Marie Ellison , Agnes Eva Hamburger , Randy Ira Hecht , Yue-Sheng Li , Mark Leo Michaels , Jeonghoon Sun , Jing Xu
- Applicant: Amgen Inc.
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Main IPC: A61K38/18
- IPC: A61K38/18 ; C07K14/50 ; C12N15/12 ; C12N15/63 ; C07K16/18 ; A61K38/00
Abstract:
The invention provides FGF21 mutant polypeptides with reduced proteolysis and aggregation, pharmaceutical compositions comprising the same.
Public/Granted literature
- US20140243503A1 FGF21 MUTANTS AND USES THEREOF Public/Granted day:2014-08-28
Information query
IPC分类:
