发明授权
- 专利标题： Methods for cloning and manipulating genomes
- 专利标题（中）： 克隆和操纵基因组的方法
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申请号： US12718911申请日： 2010-03-05
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公开(公告)号： US09273310B2公开(公告)日： 2016-03-01
- 发明人: Gwynedd A. Benders , John I. Glass , Clyde A. Hutchison, III , Carole Lartigue , Sanjay Vashee , Mikkel A. Algire , Hamilton O. Smith , Charles E. Merryman , Vladimir N. Noskov , Ray-Yuan Chuang , Daniel G. Gibson , J. Craig Venter
- 申请人： Gwynedd A. Benders , John I. Glass , Clyde A. Hutchison, III , Carole Lartigue , Sanjay Vashee , Mikkel A. Algire , Hamilton O. Smith , Charles E. Merryman , Vladimir N. Noskov , Ray-Yuan Chuang , Daniel G. Gibson , J. Craig Venter
- 申请人地址： US CA La Jolla
- 专利权人： Synthetic Genomics, Inc.
- 当前专利权人： Synthetic Genomics, Inc.
- 当前专利权人地址： US CA La Jolla
- 代理机构： DLA Piper LLP (US)
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; C12N15/10
摘要：
Compositions and methods are disclosed herein for cloning a donor genome in a heterologous host cell. In one embodiment, the donor genome can be further modified within a host cell. Modified or unmodified genomes can be further isolated from the host cell and transferred to a recipient cell. Methods disclosed herein can be used to alter donor genomes from intractable donor cells in more tractable host cells.
公开/授权文献
- US20110053272A1 METHODS FOR CLONING AND MANIPULATING GENOMES 公开/授权日：2011-03-03