A flexible substrate, a manufacturing method for the flexible substrate and an OLED display device including the flexible substrate are provided. The flexible substrate includes a flexible base on which a mesh depression layer is provided, in which a mesh current sinking layer is embedded. The mesh current sinking layer is configured to enhance electrical conductivity of the flexible substrate. With the mesh depression layer, the mesh current sinking layer may be embedded in the flexible substrate, which effectively enhances the electrical conductivity of the flexible substrate.