Invention Grant
US09284364B2 Isolated nucleic acid molecule encoding a fusion protein comprising an activin receptor
有权
分离的编码包含激活素受体的融合蛋白的核酸分子
- Patent Title: Isolated nucleic acid molecule encoding a fusion protein comprising an activin receptor
- Patent Title (中): 分离的编码包含激活素受体的融合蛋白的核酸分子
-
Application No.: US14085056Application Date: 2013-11-20
-
Publication No.: US09284364B2Publication Date: 2016-03-15
- Inventor: Huiquan Han , Keith Soo-Nyung Kwak , Xiaolan Zhou
- Applicant: Amgen Inc.
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agency: Fenwick & West LLP
- Main IPC: C12P21/06
- IPC: C12P21/06 ; C12N5/02 ; C12N15/00 ; C07K14/71
Abstract:
The present invention provides novel activin IIB5 receptor polypeptides capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the receptor polypeptides. Compositions and methods for treating muscle-wasting, metabolic and other disorders are also provided.
Public/Granted literature
- US20140088008A1 NOVEL ACTIVIN RECEPTOR AND USES THEREOF Public/Granted day:2014-03-27
Information query
