发明授权
US09284364B2 Isolated nucleic acid molecule encoding a fusion protein comprising an activin receptor
有权
分离的编码包含激活素受体的融合蛋白的核酸分子
- 专利标题： Isolated nucleic acid molecule encoding a fusion protein comprising an activin receptor
- 专利标题（中）： 分离的编码包含激活素受体的融合蛋白的核酸分子
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申请号： US14085056申请日： 2013-11-20
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公开(公告)号： US09284364B2公开(公告)日： 2016-03-15
- 发明人: Huiquan Han , Keith Soo-Nyung Kwak , Xiaolan Zhou
- 申请人： Amgen Inc.
- 申请人地址： US CA Thousand Oaks
- 专利权人： Amgen Inc.
- 当前专利权人： Amgen Inc.
- 当前专利权人地址： US CA Thousand Oaks
- 代理机构： Fenwick & West LLP
- 主分类号： C12P21/06
- IPC分类号： C12P21/06 ; C12N5/02 ; C12N15/00 ; C07K14/71
摘要：
The present invention provides novel activin IIB5 receptor polypeptides capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the receptor polypeptides. Compositions and methods for treating muscle-wasting, metabolic and other disorders are also provided.
公开/授权文献
- US20140088008A1 NOVEL ACTIVIN RECEPTOR AND USES THEREOF 公开/授权日：2014-03-27
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