Uplink power control in a macro cell in a wireless network comprises transmitting a reference signal from a base station device to at least one wireless device within the macro cell. The macro cell comprises the base station device and at least one radio transmitter device that is communicatively coupled to and remote from the base station device. The base station device and one or more radio transmitter devices could be selected to be a transmission point, a reception point or a combination thereof, for each wireless device. Information relating to a transmission power of the base station device is also transmitted to the at least one wireless device. An uplink signal is received from the at least one wireless device containing information relating to an uplink power determination that is based on the reference signal and the information relating to the transmission power of the base station device.