Invention Grant
- Patent Title: Purine derivatives
- Patent Title (中): 嘌呤衍生物
-
Application No.: US14548749Application Date: 2014-11-20
-
Publication No.: US09290496B2Publication Date: 2016-03-22
- Inventor: Douglas Carl Behenna , Hengmiao Cheng , Sujin Cho-Schultz , Theodore Otto Johnson, Jr. , John Charles Kath , Asako Nagata , Sajiv Krishnan Nair , Simon Paul Planken
- Applicant: PFIZER INC.
- Applicant Address: US NY New York
- Assignee: PFIZER INC.
- Current Assignee: PFIZER INC.
- Current Assignee Address: US NY New York
- Agent Suzanne M. Bates; Stephen D. Prodnuk
- Main IPC: A61K31/519
- IPC: A61K31/519 ; C07D473/18 ; A61P35/00 ; A61K31/5377 ; C07D498/10 ; A61K31/5386 ; C07D487/04 ; A61K31/52 ; C07D473/16 ; C07D519/00

Abstract:
The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Q, G, ring A, ring B, R1, R2, R3, R4, R5, R5a, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, R19, R20, R21, R22, R23, R24, and m are defined herein. The novel purine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. Additional embodiments relate to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.
Public/Granted literature
- US20150141402A1 PURINE DERIVATIVES Public/Granted day:2015-05-21
Information query
IPC分类: