发明授权
- 专利标题： C4 monomethyl triterpenoid derivatives and methods of use thereof
- 专利标题（中）： C4单甲基三萜衍生物及其使用方法
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申请号： US13417519申请日： 2012-03-12
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公开(公告)号： US09290536B2公开(公告)日： 2016-03-22
- 发明人: Eric Anderson , Christopher F. Bender , Xiaofeng Liu , Xin Jiang , Melean Visnick
- 申请人： Eric Anderson , Christopher F. Bender , Xiaofeng Liu , Xin Jiang , Melean Visnick
- 申请人地址： US TX Irving
- 专利权人： Reata Pharmaceuticals, Inc.
- 当前专利权人： Reata Pharmaceuticals, Inc.
- 当前专利权人地址： US TX Irving
- 代理机构： Parker Highlander PLLC
- 主分类号： C07D265/30
- IPC分类号： C07D265/30 ; A61K31/215 ; C07J63/00 ; C07J71/00
摘要：
Disclosed herein are novel C4-monomethyl triterpenoid compounds and derivatives thereof, including those of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds. Methods and intermediates useful for making the compounds, and methods of using the compounds, for example as antioxidant inflammation modulators, and compositions thereof are also provided.