发明授权
- 专利标题： Method for enucleating nucleated erythrocyte, and enucleation inducer
- 专利标题（中）： 去核成核红细胞和去核诱导剂的方法
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申请号： US13202852申请日： 2010-02-23
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公开(公告)号： US09290737B2公开(公告)日： 2016-03-22
- 发明人: Toshihisa Hatta , Eriko Shimamura , Hiroki Shimada
- 申请人： Toshihisa Hatta , Eriko Shimamura , Hiroki Shimada
- 申请人地址： JP Ishikawa
- 专利权人： Kanazawa Medical University
- 当前专利权人： Kanazawa Medical University
- 当前专利权人地址： JP Ishikawa
- 代理机构： Kilyk & Bowersox, P.L.L.C.
- 优先权： JP2009-040781 20090224
- 国际申请： PCT/JP2010/001217 WO 20100223
- 国际公布： WO2010/098079 WO 20100902
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C12N5/078 ; C07K14/665 ; C07K14/00 ; C07K7/00
摘要：
Provided is a factor capable of inducing enucleation, which is a final stage of erythrocyte differentiation, within a short time. More particularly, provided are a method of inducing enucleation, which is a final stage of erythrocyte differentiation, within a short time by adding a compound derived from proopiomelanocortin (POMC) to an undifferentiated (nucleated) erythrocyte, and an enucleation inducer including the compound.