The present invention provides an array substrate, a manufacturing method thereof and a display panel. The array substrate comprises a base, the base comprises a display region for displaying and a periphery region outside the display region, a plurality of lead wires extending from the display region to the periphery region are provided on a first side of the base, a plurality of conductive via-holes are provided in the periphery region of the base, the conductive via-holes are electrically connected with the respective lead wires and provided with conductive material therein, the lead wires are electrically connected to a second side of the base through the respective conductive via-holes; a back-side structure electrically connected with the conductive via-holes is provided on the second side of the base, and the back-side structure comprises a plurality of lead wire pads electrically connected with the respective conductive via-holes.