发明授权
US09295673B2 Combination of mTOR inhibitors and P13-kinase inhibitors, and uses thereof
有权
mTOR抑制剂和P13-激酶抑制剂的组合及其用途
- 专利标题： Combination of mTOR inhibitors and P13-kinase inhibitors, and uses thereof
- 专利标题（中）： mTOR抑制剂和P13-激酶抑制剂的组合及其用途
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申请号： US13403856申请日： 2012-02-23
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公开(公告)号： US09295673B2公开(公告)日： 2016-03-29
- 发明人: Pingda Ren , Yi Liu , Katayoun Jessen , Xin Guo , Christian Rommel , Troy Edward Wilson
- 申请人： Pingda Ren , Yi Liu , Katayoun Jessen , Xin Guo , Christian Rommel , Troy Edward Wilson
- 申请人地址： US CA La Jolla
- 专利权人： Intellikine LLC
- 当前专利权人： Intellikine LLC
- 当前专利权人地址： US CA La Jolla
- 代理机构： Honigman Miller Schwartz and Cohn LLP
- 代理商 Lucy X. Yang; Jonathan P. O'Brien
- 主分类号： A61K31/551
- IPC分类号： A61K31/551 ; A61K31/4439 ; A61K31/4745 ; A61K31/498 ; A61K45/06 ; A61K31/501 ; A61K31/517 ; A61K31/519 ; A61K31/527 ; A61K31/53 ; A61K31/5377 ; A61K31/541
摘要：
The present invention provides for a method for treating a disease condition associated with PI3-kinase α and/or mTOR in a subject. In another aspect, the invention provides for a method for treating a disease condition associated with PI3-kinase α and/or mTOR in a subject. In yet another aspect, a method of inhibiting phosphorylation of both Akt (S473) and Akt (T308) in a cell is set forth.
公开/授权文献
- US20120294930A1 COMBINATION OF KINASE INHIBITORS AND USES THEREOF 公开/授权日：2012-11-22