Bicyclo (3.1.0) hexane-2, 6-dicarboxylic acid derivatives as mGlu2 receptor agonist

Invention Grant

US09296710B2 Bicyclo (3.1.0) hexane-2, 6-dicarboxylic acid derivatives as mGlu2 receptor agonist 有权

Title translation: 双环（3.1.0）己烷-2,6-二羧酸衍生物作为mGlu2受体激动剂

Patent Title: Bicyclo (3.1.0) hexane-2, 6-dicarboxylic acid derivatives as mGlu2 receptor agonist
Patent Title (中): 双环（3.1.0）己烷-2,6-二羧酸衍生物作为mGlu2受体激动剂
Application No.: US14123768

Application Date: 2012-06-07
Publication No.: US09296710B2

Publication Date: 2016-03-29
Inventor: Teresa Tse Ki Man , James Allen Monn , Carlos Montero Salgado , Lourdes Prieto , David Edward Tupper , Lesley Walton
Applicant: Teresa Tse Ki Man , James Allen Monn , Carlos Montero Salgado , Lourdes Prieto , David Edward Tupper , Lesley Walton
Applicant Address: US IN Indianapolis
Assignee: Eli Lilly and Company
Current Assignee: Eli Lilly and Company
Current Assignee Address: US IN Indianapolis
Agent R. Craig Tucker; Danica Hostettler
Priority: EP11382208 20110617
International Application: PCT/US2012/041229 WO 20120607
International Announcement: WO2012/173850 WO 20121220
Main IPC: C07D249/04
IPC: C07D249/04 ; C07D249/12 ; C07D249/14

Abstract:

The present invention provides novel mGlu2 agonists useful in the treatment of bipolar disorder, schizophrenia, and generalized anxiety disorder.

Abstract(Chinese):

本发明提供了可用于治疗双相障碍，精神分裂症和广泛性焦虑症的新型mGlu2激动剂。

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