Invention Grant
- Patent Title: Spirolactam CGRP receptor antagonists
- Patent Title (中): 螺内酰胺CGRP受体拮抗剂
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Application No.: US14399438Application Date: 2013-05-03
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Publication No.: US09296750B2Publication Date: 2016-03-29
- Inventor: Ian M. Bell , Mark Fraley , Tesfaye Biftu , Cheng Zhu , Anilkumar Nair
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent H. Eric Fischer; John C. Todaro
- International Application: PCT/US2013/039364 WO 20130503
- International Announcement: WO2013/169567 WO 20131114
- Main IPC: C07D471/10
- IPC: C07D471/10 ; C07D491/22 ; C07D471/04 ; C07D491/107 ; C07D491/20
Abstract:
The present invention is directed to spirolactam analogs which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
Public/Granted literature
- US20150111914A1 SPIROLACTAM CGRP RECEPTOR ANTAGONISTS Public/Granted day:2015-04-23
Information query
