Invention Grant
- Patent Title: Spiro-oxindole MDM2 antagonists
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Application No.: US14170101Application Date: 2014-01-31
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Publication No.: US09302120B2Publication Date: 2016-04-05
- Inventor: Shaomeng Wang , Yujun Zhao , Wei Sun
- Applicant: The Regents of the University of Michigan
- Applicant Address: US MI Ann Arbor
- Assignee: The Regents of the University of Michigan
- Current Assignee: The Regents of the University of Michigan
- Current Assignee Address: US MI Ann Arbor
- Agency: Casimir Jones, SC
- Main IPC: C07D487/10
- IPC: C07D487/10 ; A61N5/10 ; A61K31/407 ; A61K45/06
Abstract:
Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases.
Public/Granted literature
- US20140148494A1 SPIRO-OXINDOLE MDM2 ANTAGONISTS Public/Granted day:2014-05-29
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